I recently migrated this blog to a new server running CentOS 7 and decided to use php-fpm and mod_proxy_fcgi instead of mod_php. I also like to install WordPress in its own directory and had problems getting the wp-admin sections of the site to work. I figured it out eventually with help from this page: https://wiki.apache.org/httpd/PHPFPMWordpress

This is the complete apache config fragment that defines the vhost, including SSL:

<VirtualHost *:443>
  ServerName blog.yo61.com

  ## Vhost docroot
  DocumentRoot "/var/www/sites/blog.yo61.com/html"

  ## Directories, there should at least be a declaration for /var/www/sites/blog.yo61.com/html

  <Directory "/var/www/sites/blog.yo61.com/html">
    AllowOverride FileInfo
    Require all granted
    DirectoryIndex index.php
    FallbackResource /index.php
  </Directory>

  <Directory "/var/www/sites/blog.yo61.com/html/wordpress/wp-admin">
    AllowOverride None
    Require all granted
    FallbackResource disabled
  </Directory>

  ## Logging
  ErrorLog "/var/log/httpd/blog.yo61.com_https_error_ssl.log"
  ServerSignature Off
  CustomLog "/var/log/httpd/blog.yo61.com_https_access_ssl.log" combined

  ## SSL directives
  SSLEngine on
  SSLCertificateFile      "/etc/letsencrypt/live/blog.yo61.com/cert.pem"
  SSLCertificateKeyFile   "/etc/letsencrypt/live/blog.yo61.com/privkey.pem"
  SSLCertificateChainFile "/etc/letsencrypt/live/blog.yo61.com/chain.pem"
  SSLCACertificatePath    "/etc/pki/tls/certs"

  ## Custom fragment
  ProxyPassMatch ^/(.*\.php(/.*)?)$ fcgi://127.0.0.1:9000/var/www/sites/blog.yo61.com/html/$1
  Header always set Strict-Transport-Security "max-age=63072000; includeSubdomains; preload"
  Header always set X-Frame-Options DENY
  Header always set X-Content-Type-Options nosniff
</VirtualHost>